The invention provides a nanofiltration concentrating purifying device for organic matter dissolved in water. The device comprises a raw water supply unit, a pretreatment unit, a nanofiltration concentrating unit, a pH value regulating unit, an end product liquid extracting unit, a water tank and a master control system, wherein the end product liquid extracting unit comprises an absorption enriching device, an ion exchange device, a leaching device and an alkali liquor drug box; the leaching device and the alkali liquor drug box are arranged in parallel; an inlet of the absorption enriching device is connected with an outlet of the water tank, the outlet of the leaching device and the outlet of the alkali liquor drug box; the outlet of the absorption enriching device is connected with the inlet of the ion exchange device; the absorption enriching device and the ion exchange device in the end product liquid extracting unit are adopted for absorbing, enriching and purifying the organic matter dissolved in concentrated water and extracting the required liquid. The nanofiltration concentrating purifying device for organic matter dissolved in water provided by the invention is suitable for seawater and fresh water, the structure is simple, the operation is convenient and the yield is high.