The invention discloses a novel side-vertical integrated installation mechanism of a sliding-plug door. The novel side-vertical integrated installation mechanism comprises an installation bottom plate which is vertically arranged, wherein a door vertical-hood fixing plate and a vertical side baffle plate are arranged in a way of being vertical to the installation bottom plate; the installation bottom plate is provided with an upper-part wire binding pole and a middle-part wire binding pole in sequence from top to bottom; the door vertical-hood fixing plate is provided with a side-part wire binding pole, a side-surface upper baffle plate and a side-surface lower baffle plate in sequence from top to bottom. Compared with the prior art, the novel side-vertical integrated installation mechanism disclosed by the invention has the advantages that by an integrated design, the installation bottom plate, the door vertical-hood fixing plate, the vertical side baffle plate, the upper-part wire binding pole, the middle-part wire binding pole, the side-part wire binding pole, the side-surface upper baffle plate and the side-surface lower baffle plate are integrated into a whole body, so that convenience is brought for fixing all components and elements in the sliding-plug door of a coach; compared with the original distributed type installation mode, the assembling efficiency is improved by at least ten times, and the assembling quality and the appearance effect are obviously improved.