The invention belongs to the field of pretreatment devices of analytical instruments and discloses a portable efficient magnetic solid-phase extraction device. The device mainly comprises a contact reaction chamber, a circulating water inlet, a clear water tank, a circulating pump, a circulating water outlet, a solid-phase extraction agent collection tank, a magnetic support, a electromagnet, a solid-liquid separation zone, a drain valve, a wall spraying water inlet and a wall spraying pipe, wherein the contact reaction chamber is conical, adopts hydraulic stirring and guarantees contact stirring without a dead angle; the action areas of a magnetic solid-phase extraction agent and the electromagnet are increased by the aid of the solid-liquid separation zone in a reversed conical shape; the solid-phase extraction agent collection tank adopts a downward bulging dish shape so as to prevent run-off of the solid-phase extraction agent; the device is additionally equipped with the wall spraying pipe, so that the solid-phase extraction agent is prevented from remaining in the contact reaction chamber; the solid-phase extraction agent in a pipeline is completely collected by the clear water tank. The portable efficient magnetic solid-phase extraction device can realize efficient collection of the magnetic solid-phase extraction agent, effectively guarantees the recovery rate of solid-phase extraction, meets the requirement of different enrichment times, greatly shortens the extraction time and is carried conveniently to a field for use.