The invention discloses a montelukast orally disintegrating tablet. The montelukast orally disintegrating tablet is prepared from montelukast microspheres and pharmaceutically acceptable excipients and is prepared by a powder direct pressing method or a dry method for granulating and tabletting. Particularly, the montelukast microspheres are formed by combining montelukast with high polymer materials, an opacifying agent and an antisticking agent. The pharmaceutically acceptable excipients comprise a filling agent, a binding agent, a disintegrating agent, a lubricating agent and a corrigent. The montelukast orally disintegrating tablet disclosed by the invention is stable in property, is proper in mouthfeel and can be taken under the condition of no water; the property that the montelukast is optically unstable is greatly improved, and the compliance of an allergic sufferer is remarkably improved. The montelukast orally disintegrating tablet disclosed by the invention is simple in preparation process and low in production cost; the industrial demand can be met.