The invention discloses fructus cnidii health preserving wine. The fructus cnidii health preserving wine is made from, by weight, 15-30 parts of herba cistanche, 15-25 parts of radix polygoni multiflori, 15-30 parts of Chinese wolfberry fruit, 15-20 parts of radix achyranthis bidentatae, 10-20 parts of poria cocos, 10-20 parts of radix ophiopogonis, 10-15 parts of fructus psoraleae, 5-15 parts of radix angelica sinensis, 15-25 parts of mulberry fruit, 4-8 parts of safflower, 4-6 parts of fructus gardeniae, 4-6 parts of red yeast rice, 30-60 parts of kdzuvine roots, 2-10 parts of ginseng, 4-12 parts of milkvetch roots, 3-11 parts of poria with hostwood, 7-15 parts of rhizoma atractylodis macrocephalae, 6-14 parts of radix rehmanniae preparata, 8-16 parts of radix rehmanniae, 6-14 parts of radix codonopsis, 9-17 parts of rock candies, 28-36 parts of baijiu, 20-40 parts of mulberry fruit, 1-2 parts of cornu cervi pantotrichum and 15-25 parts of fructus cnidii. According to the fructus cnidii health preserving wine, the health-care functions of nourishing, health preserving and the like are achieved, production processes are simple, the production cost is reduced, and the large-scale production requirements are met.