A device (100) for measuring a plurality of parameters of a patient subject to a treatment with radiopharmaceuticals comprises a main body (101) constrained to the patient's body (50) in such a way that the measurement device (100) is of wearable type. The device (100) comprises a plurality of measurement modules, for example a first module (70) and a second module (71), each of which is equipped with a respective sensor (110,111), configured to measure a predetermined parameter of the patient (50). The device (100) is also equipped with a microprocessor (150) configured to process a plurality of data measured by the plurality of sensors (110,111), obtaining a plurality of processed data. Furthermore, a transmission means is provided of wireless type arranged to send via wireless communication the data processed by the microprocessor (150) to a remote control unit (250). The device (100) provides at least one measurement module (70) of radiations. This is equipped with a sensor (110) of radiations configured to measure the radiations emitted by the patient's body in a predetermined time range At and to determine the time of discharge tb of said patient subject to said radiopharmaceutical treatment.