![单个囊泡融合和回收及其与钙离子通道耦合的膜片钳检测装置](/CN/2015/1/20/images/201510104564.jpg)
基本信息:
- 专利标题: 单个囊泡融合和回收及其与钙离子通道耦合的膜片钳检测装置
- 申请号:CN201510104564.4 申请日:2015-03-10
- 公开(公告)号:CN106033069B 公开(公告)日:2019-05-28
- 发明人: 陈培华 , 孙坚原 , 申雪峰 , 戴金叶 , 张树利
- 申请人: 中国科学院生物物理研究所
- 申请人地址: 北京市朝阳区大屯路15号
- 专利权人: 中国科学院生物物理研究所
- 当前专利权人: 中国科学院生物物理研究所
- 当前专利权人地址: 北京市朝阳区大屯路15号
- 代理机构: 中科专利商标代理有限责任公司
- 代理人: 王旭
- 主分类号: G01N27/22
- IPC分类号: G01N27/22
The invention discloses a patch clamp detection apparatus of single vesicle fusion and recovery and coupling between single vesicle fusion and recovery and a calcium ion channel, and belongs to the field of detection instruments for neurobiology research. The patch clamp detection apparatus is controlled by computer program and comprises a capacitance detection module, a calcium ion single channel current detection module, and a measuring platform. The provided patch clamp detection apparatus is used to detect the dynamic characteristics of single vesicle fusion and recovery, current characteristics of calcium ion single channel, and dynamic characteristics of coupling between single vesicle fusion and recovery and a calcium ion channel; the detection is direct, quantitative, and realtime, and the time resolution, signal-noise ratio, and precision are high.
公开/授权文献:
- CN106033069A 单个囊泡融合和回收及其与钙离子通道耦合的膜片钳检测装置 公开/授权日:2016-10-19