![一种Keggin结构杂多酸含磷有机盐类化合物、制备方法和应用](/CN/2016/1/65/images/201610327268.jpg)
基本信息:
- 专利标题: 一种Keggin结构杂多酸含磷有机盐类化合物、制备方法和应用
- 专利标题(英):Keggin-structure heteropolyacid phosphorus-containing organic salt compound as well as preparation method and application
- 申请号:CN201610327268.5 申请日:2016-05-17
- 公开(公告)号:CN105968134A 公开(公告)日:2016-09-28
- 发明人: 闫红 , 孙武积 , 高磊 , 胡秦 , 艾萍
- 申请人: 北京工业大学
- 申请人地址: 北京市朝阳区平乐园100号
- 专利权人: 北京工业大学
- 当前专利权人: 北京工业大学
- 当前专利权人地址: 北京市朝阳区平乐园100号
- 代理机构: 北京思海天达知识产权代理有限公司
- 代理人: 张慧
- 主分类号: C07F9/11
- IPC分类号: C07F9/11 ; C07F9/165 ; C07F9/6561 ; C07F9/6584 ; A61P31/18 ; C01G41/00 ; C30B29/54
The invention discloses a Keggin-structure heteropolyacid phosphorus-containing organic salt compound as well as a preparation method and application, belonging to the field of chemical synthesis and medicinal application. The general formula of the compound disclosed by the invention is A7PTi2W10O40, wherein A is organic cation containing phosphorus and nitrogen; and the compound is a heteropolyacid compound with a Keggin structure. The preparation method comprises the following steps: dissolving sodium tungstate and sodium dihydrogen phosphate in distilled water; dropwise adding titanium tetrachloride for a reflux reaction; filtering; adding alkali metal salt or amino acid salt into the filtrate to obtain a white precipitate; recrystallizing the precipitate with hot water; adjusting to acidity with a compound containing A group or an A compound; and heating and stirring to obtain the Keggin-structure heteropolyacid phosphorus-containing organic salt compound. The compound can be used for preparing anti-HIV drugs.
公开/授权文献:
- CN105968134B 一种Keggin结构杂多酸含磷有机盐类化合物、制备方法和应用 公开/授权日:2018-03-30
IPC结构图谱:
C | 化学;冶金 |
--C07 | 有机化学 |
----C07F | 含除碳、氢、卤素、氧、氮、硫、硒或碲以外的其他元素的无环,碳环或杂环化合物 |
------C07F9/00 | 含周期表第Ⅴ族元素的化合物 |
--------C07F9/02 | .磷化合物 |
----------C07F9/06 | ..无P—C键的 |
------------C07F9/08 | ...磷的含氧酸的酯 |
--------------C07F9/09 | ....磷酸的酯 |
----------------C07F9/11 | .....与羟烷基化合物,在烷基上没有进一步的取代基 |