![一种盐酸文拉法辛的有关物质及其分析检测方法](/CN/2016/1/48/images/201610240989.jpg)
基本信息:
- 专利标题: 一种盐酸文拉法辛的有关物质及其分析检测方法
- 专利标题(英):Related substances of venlafaxine hydrochloride and analysis and detection method of related substances
- 申请号:CN201610240989.2 申请日:2016-04-18
- 公开(公告)号:CN105884630A 公开(公告)日:2016-08-24
- 发明人: 潘立 , 李义高 , 李小彪 , 赵阳
- 申请人: 镇江高海生物药业有限公司
- 申请人地址: 江苏省镇江市丹徒区高桥镇工业集中区
- 专利权人: 镇江高海生物药业有限公司
- 当前专利权人: 镇江高海生物药业有限公司
- 当前专利权人地址: 江苏省镇江市丹徒区高桥镇工业集中区
- 代理机构: 南京汇盛专利商标事务所
- 代理人: 陈扬
- 主分类号: C07C217/74
- IPC分类号: C07C217/74 ; C07C213/08 ; C07C213/10 ; G01N30/02
The invention discloses related substances of venlafaxine hydrochloride and an analysis and detection method of the related substances. A new venlafaxine hydrochloride photodegradation product is found, and the structure of the degradation product is reported for the first time. The preparation method of the photodegradation product is simple and easy to implement and can be used for preparing the degradation product on a large scale. The degradation product can be quickly detected with a liquid-phase analysis method, the maximum absorption wavelength of the degradation product is taken as a detection wavelength, the detection rate of the degradation product is increased, and results are accurate and reliable. The photodegradation product can be used for checking the related substances of venlafaxine hydrochloride and preparations of venlafaxine hydrochloride, the quality standards of venlafaxine hydrochloride and preparations of venlafaxine hydrochloride are further improved, and the safety and the controllability are improved.
公开/授权文献:
- CN105884630B 一种盐酸文拉法辛的有关物质及其分析检测方法 公开/授权日:2018-06-01
IPC结构图谱:
C | 化学;冶金 |
--C07 | 有机化学 |
----C07C | 无环或碳环化合物 |
------C07C217/00 | 连接在同一个碳架上的含氨基和醚化的羟基的化合物 |
--------C07C217/54 | .醚化的羟基连接在至少1个六元芳环的碳原子上和氨基连接在非环碳原子上或连接在除同一个碳架的六元芳环以外的其他环的碳原子上 |
----------C07C217/74 | ..有是碳架组成部分的除六元芳环以外的其他环 |