A novel scrawl-preventing self-cleaning polytetrafluoroethylene vanish for an aluminum-plastic composite panel is prepared from, by mass, 70-85% of tetrafluoroethylene resin, 5-10% of amino resin, 0.1-0.3% of an acid catalyst, 0.5-1.0% of an antioxidant, 0.5-1.0% of an ultraviolet light absorber, 2-3% of other assistants and 5-10% of a mixed solvent.According to the self-cleaning principle of lotus leaves, a layer of scrawl-preventing self-cleaning vanish is smeared on the surface of an original polyester or fluorocarbon or acrylic acid coating so that dust and the like can hardly be adsorbed on the coating; besides, sprayed ink and markers used for scrawling on the coating cannot be attached to the surface of an object easily, and pasted adlets can peel off naturally; thus, the product solves the problems of chaos pasting and scrawling, and when the product is applied to the aluminum-plastic composite panel, the service life of a building curtain wall can be prolonged, and the functions of weatherability, acid-base resistance, acid rain resistance, weathering pollution resistance, waterproofing and the like are enhanced.