The invention provides a setting management method and system of a dividing switch of a 10kv distribution line. According to the method, the obtained dividing switch equipment parameters are sent to the management system; dividing switch fixed values are set by the management system according to the setting principle and all the dividing switch equipment parameters; after the dividing switches of the required dividing switch fixed value are confirmed, the setting calculation of the required dividing switch can be completed and required dividing switch setting lists can be automatically generated by the management system with no need for manual calculation, so that the method is high in work efficiency and low in error rate, the workload of power grid protecting professional setting staff is greatly reduced, the reliability and the standard degree of the dividing switch setting lists and the management process are increased; the dividing switch setting lists confirmed to be correct are filed in the management system after dividing switch checking, so that the dividing switch setting lists can be conveniently unified and consulted by all departments in the power system, the maintenance and the share of the dividing switch setting list protecting information among the different departments are benefited; and the unified standard management of the whole power equipment is benefited.