The invention provides a bullet-proof composite plate and a manufacturing method thereof. The defects that the attaching tightness is poor, the technology is complex, the manufacturing efficiency is low and the manufacturing cost is high when traditional ceramic multi-surface nonisotropic plates and high-performance fiber composite material plates are combined are overcome. The overall bullet-proof performance of the ceramic bullet-proof composite plate is improved, multi-surface nonisotropic ceramic plates, hot-melting adhesive membranes and high-performance fiber composite material plates are directly stacked together and placed into a vacuum device for vacuum pressing, the problem that the cost is too high in the repeated pressing process is avoided, and the defect that the multi-surface nonisotropic ceramic plates and the high-performance fiber composite material plates cannot be tightly attached is overcome; and the finished product rate and the production efficiency are improved, and the overall bullet-proof efficiency of the bullet-proof composite plate is enhanced. The one-time molding technology is adopted, and the one-time molding technology is easier, faster and more convenient to implement than the traditional technology that high-performance fiber composite material layers are pressed and attached to ceramic successively.