![在侧流免疫分析中产生pH/温度/离子梯度用于调节生物分子的相互作用及其应用](/CN/2014/8/2/images/201480013758.jpg)
基本信息:
- 专利标题: 在侧流免疫分析中产生pH/温度/离子梯度用于调节生物分子的相互作用及其应用
- 专利标题(英):Generation of pH/temperature/ionic gradients in lateral flow immunoassays for modulating biomolecular interactions and its applications
- 申请号:CN201480013758.7 申请日:2014-03-12
- 公开(公告)号:CN105263628A 公开(公告)日:2016-01-20
- 发明人: C·约翰逊 , S·卡伍斯 , H·艾哈迈德 , C·朗
- 申请人: 罗伯特·博世有限公司
- 申请人地址: 德国斯图加特
- 专利权人: 罗伯特·博世有限公司
- 当前专利权人: 罗伯特·博世有限公司
- 当前专利权人地址: 德国斯图加特
- 代理机构: 永新专利商标代理有限公司
- 代理人: 彭丽丹; 过晓东
- 优先权: 13/800,328 2013.03.13 US
- 国际申请: PCT/US2014/024760 2014.03.12
- 国际公布: WO2014/165198 EN 2014.10.09
- 进入国家日期: 2015-09-10
- 主分类号: B01L3/00
- IPC分类号: B01L3/00 ; G01N33/50
Lateral flow assay devices comprising a multisite array of test sites (8) for measuring a biomolecule analyte (3) having a solid support (5) including absorbent material for providing capillary flow, one device being divided into parallel lanes (7) in the flow direction. The devices comprising a sample portion for receiving a sample; a diagnostic portion comprising a multisite array of test sites (8) each comprising a probe for the biomolecular analyte (3), wherein at each test site of the multisite array the conditions for the interaction between the biomolecular analyte and the probe can be varied independently; an absorbent portion of absorbent material for providing capillary flow; and electrodes (10) for actuating and controlling conditions. The sample portion, diagnostic portion, and absorbent portion are in capillary flow communication resulting in a capillary flow from sample portion towards absorbent portion, whereby the sample flows across the probe at each test site in the diagnostic portion to provide contact between the sample and such probe. Methods for measuring analyte concentration in a sample using such lateral flow assay devices.
公开/授权文献:
- CN105263628B 在侧流免疫分析中产生pH/温度/离子梯度用于调节生物分子的相互作用及其应用 公开/授权日:2018-04-24
IPC结构图谱:
B | 作业;运输 |
--B01 | 一般的物理或化学的方法或装置 |
----B01L | 通用化学或物理实验室设备 |
------B01L3/00 | 实验室用的容器或器皿,如实验室玻璃仪器(瓶子入B65D;酶或微生物学用的设备入C12M1/00);点滴器 |