The invention discloses a high-speed patrol ship which comprises a ship body, wherein the ship body is divided into an upper part space and a lower part space by a deck; a command cabin and a cab are positioned in the upper part space; the lower part space positioned at the tail of the ship body is sequentially provided with a ballast cabin, a fuel cabin and a main engine cabin; the main engine cabin is internally provided with a first main engine and a second main engine which drive corresponding gear boxes to drive corresponding propellers to rotate respectively; rotation directions of the first main engine and the second main engine are opposite; a sailor rest cabin is arranged beside the main engine cabin; the main engine cabin is internally provided with a steering engine cabin; and the steering engine cabin is internally provided with a steering engine. With the adoption of the two main engines and the two propellers to propel, and the positive and negative rotation of the two main engines, the flexibility and the maneuverability of ship operation are improved; with the adoption of the low-power main engines, the invested cost is little, and the maintenance is convenient; and wave suppression strips are arranged at two ship boards of a bow of the high-speed patrol ship, and wave blocking plates are arranged at the ship bottom of the tail of the high-speed patrol ship, so that the arrangement is reasonable, a navigational speed is increased effectively, and the cabins are compact in design.