
基本信息:
- 专利标题: 脓毒症多种致病因子的吸附材料及其制备方法和用途
- 专利标题(英):Adsorbing material for multiple pathogenic factors of sepsis as well as preparation method and application of adsorbing material
- 申请号:CN201510717518.1 申请日:2015-10-29
- 公开(公告)号:CN105195114A 公开(公告)日:2015-12-30
- 发明人: 郑玥 , 邓军 , 刘清光
- 申请人: 重庆安体新生物技术有限公司
- 申请人地址: 重庆市沙坪坝区兰美路1200号凤鸣香山小区2幢16-2号
- 专利权人: 重庆安体新生物技术有限公司
- 当前专利权人: 重庆郑博生物科技有限公司
- 当前专利权人地址: 重庆市沙坪坝区兰美路1200号凤鸣香山小区2幢16-2号
- 代理机构: 重庆志合专利事务所
- 代理人: 胡荣珲
- 主分类号: B01J20/26
- IPC分类号: B01J20/26 ; B01J20/30 ; A61M1/34
摘要:
本发明涉及一种脓毒症的多种致病因子的吸附材料及制备方法和用途。该吸附材料由具有良好机械性能及血液相容性的载体和具有吸附多种病原体相关分子能力的配基偶联而成,能够有效地从血液等流体中吸附细菌内毒素、细菌基因组DNA、肽聚糖、磷壁酸、病毒RNA以及酵母多糖,特别在脓毒症的血液净化治疗中具有重要应用价值。
摘要(英):
The invention relates to an adsorbing material for multiple pathogenic factors of sepsis as well as a preparation method and an application of the adsorbing material. The adsorbing material is formed by coupling a carrier with good mechanical performance and blood compatibility and a ligand with capacity of adsorbing multiple pathogen associated molecules, can effectively adsorb bacterial endotoxin, bacterial genome DNA (deoxyribonucleic acid), peptidoglycan, teichoic acid virus RNA (ribonucleic acid) and zymosan from fluids such as blood and the like, and has great application value in blood purification treatment of sepsis.
公开/授权文献:
- CN105195114B 脓毒症多种致病因子的吸附材料及其制备方法和用途 公开/授权日:2017-08-25