基本信息:
- 专利标题： 以混合生育酚为原料制备α-生育酚的方法
- 专利标题（英）：Method for using mixed tocopherol as raw material to prepare alpha-tocopherol
- 申请号：CN201510639394.X 申请日：2015-09-30
- 公开(公告)号：CN105153102A 公开(公告)日：2015-12-16
- 发明人： 孙海辉 , 张昭 , 叶留平 , 谢刚 , 李广明
- 申请人： 宜春大海龟生命科学有限公司
- 申请人地址： 江西省宜春市袁州区医药工业园
- 专利权人： 宜春大海龟生命科学有限公司
- 当前专利权人： 宜春大海龟生命科学有限公司
- 当前专利权人地址： 江西省宜春市袁州区医药工业园
- 代理机构： 北京汇泽知识产权代理有限公司
- 代理人： 张瑾
- 主分类号： C07D311/72
- IPC分类号： C07D311/72
The invention discloses a method for using mixed tocopherol as a raw material to prepare alpha-tocopherol. The mixed tocopherol is used as the raw material, methyl alcohol is used as a solvent, an alkyl agent is used for conducting alkyl substitution reaction on H atoms on a benzene ring in the mixed tocopherol in the presence of a catalyst and obtaining corresponding alpha-tocopherol through conversion, the catalyst and the solvent are removed and the alpha-tocopherol is obtained after reaction. When the catalyst is lewis acid, the alkyl agent is CH3C1, CH3Br or CH3I. When the catalyst is protonic acid, the alkyl agent is the methyl alcohol. The preparation method only needs one-step reaction, a preparation process is simplified, the requirements for reaction conditions are also low, the production and investment costs are low, and the method facilitates industrial large-scale production.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D311/00 | 杂环化合物，含六元环，有1个氧原子作为仅有的杂环原子，与其他环稠合 |
| --------C07D311/02 | .与碳环或碳环系邻位或迫位稠合 |
| ----------C07D311/04 | ..苯并 |
| ------------C07D311/06 | ...有氧原子或硫原子直接连在位置2上 |
| --------------C07D311/70 | ....有两个烃基连在位置2及除碳和氢以外的元素连在位置6 |
| ----------------C07D311/72 | .....3，4-二氢化衍生物，至少在位置2有1个甲基和在位置6有1个氧原子，例如维生素E |