The invention discloses a method for preparing cynanchum wallichii wight total saponins. The method for preparing the cynanchum wallichii wight total saponins comprises the following steps that after cynanchum wallichii wight medicinal materials are smashed, continuous reflux extraction is conducted by means of solvent, extracted solutions are mixed and are concentrated to be in an extractum shape, hot dissolving is conducted by adding water, extraction is conducted twice by means of petroleum ether, and water layers are combined, so that a water solution is obtained; a polyamide column is added to the water solution, and elution is conducted by means of solvent; a macroporous resin column is added to effluent obtained after polyamide is eluted, and elution is conducted by means of purified water, 20% ethyl alcohol and 95% ethyl alcohol, the 95% ethyl alcohol part is recovered, and 95% ethyl alcohol part is dissolved out by means of proper solvent after being concentrated into extractum; a silica gel column is added when digested liquor is diluted to be at a proper concentration, elution is conducted in sequence by means of different kinds of elution solvents, after thin-layer monitoring, effluents containing cynanchum wallichii wight saponin is mixed, the mixture is dried through concentration, and then the cynanchum wallichii wight total saponins are obtained. According to the method for preparing the cynanchum wallichii wight total saponins, the advantages of the macroporous resin and polyamide technique are adopted, cost of equipment and materials is low, the technological processes are clear, the processing capacity is high, operation is easy and convenient, the chromaticity of products is high, the yield and the content are high, and the method is suitable for industrial mass production.