基本信息:
- 专利标题： 一种阿立哌唑纳米晶体及其制备方法
- 专利标题（英）：Aripiprazole nanocrystal and preparation method thereof
- 申请号：CN201510350199.5 申请日：2015-06-24
- 公开(公告)号：CN104906038A 公开(公告)日：2015-09-16
- 发明人： 冯思欣 , 马莉
- 申请人： 万特制药(海南)有限公司
- 申请人地址： 海南省海口市秀英区南海大道279号
- 专利权人： 万特制药(海南)有限公司
- 当前专利权人： 万特制药(海南)有限公司
- 当前专利权人地址： 海南省海口市秀英区南海大道279号
- 主分类号： A61K9/10
- IPC分类号： A61K9/10 ; A61K31/496 ; A61P25/18
The invention belongs to the field of medicines and in particular relates to aripiprazole nanocrystal suspension and a preparation method thereof. Concretely, the nanocrystal suspension is composed of active ingredients such as aripiprazole, a stabilizing agent and an antiseptic substance; and the preparation method of the nanocrystal suspension adopts one or a combination of more than one of a precipitation method, an emulsification method, a high pressure homogenization method, a medium milling method and a high pressure microjet method. The nanocrystal suspension provided by the invention can be used for effectively solving the problem that solubility of aripiprazole is low, can mask bitter, astringent and pungent tastes of aripirazole and has a good market prospect.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K9/00 | 以特殊物理形状为特征的医药配制品 |
| --------A61K9/10 | .分散液；乳剂 |