The invention relates to a location tooling, in particular to a locomotive guide flange location tooling. The location tooling comprises a main frame, a longitudinal support, first longitudinal supports, location nail seats, longitudinal central line location nails, second longitudinal supports, a cross central line location nail, cross supports, a pressing block, a guide flange location seat, lifting lugs, first datum plates, second datum plates and jacking screws. The location nail seats, the longitudinal support, the first longitudinal supports, the lifting lugs and the first datum plates are arranged on longitudinal beams of the main frame. The longitudinal central line location nails are sleeved in the location nail seats, the jacking screws are sleeved in the first longitudinal supports, the jacking screws are arranged on the longitudinal support, the pressing blocks are arranged at the top ends of the jacking screws, the second longitudinal supports are arranged on middle beams of the main frame, compression screws are arranged on the second longitudinal supports, and the cross central line location nail, the cross supports, the guide flange location seat and the second datum plates are arranged on a beam of the main frame. By means of the location tooling, technological requirements are met, the practicality is high, and the location tooling is an unnecessary tooling in production.