The invention discloses a core wire welding opening processing method of a 2M radio frequency coaxial connector and relates to the core wire welding opening processing method of the 2M radio frequency coaxial connector. The invention aims at solving the technical problem that core wire welding openings of most existing 2M radio frequency coaxial connectors are narrow. According to the method, a tie bar baffle at one side of a core wire welding opening of the 2M radio frequency coaxial connector is removed from tie bar baffles at two sides; the core wire welding opening of the 2M radio frequency coaxial connector is rotated to enable the reverse side of the core wire welding opening of the 2M radio frequency coaxial connector to face towards the tie bar baffle at the other side. The core wire welding opening processing method of the 2M radio frequency coaxial connector has the advantages that the welding work is facilitated, materials are saved, the welding work of the 2M radio frequency coaxial connector and a 2M cable is simplified, the work efficiency and the welding quality are improved, the degree of freedom of an electric soldering iron during welding is expanded from original necessary vertical welding to free welding within the range of 270 degrees, and convenience is provided for working procedure manufacturing in the field.