The invention provides a preparation method of a shaped charge liner tantalum 5 tungsten material. The preparation method comprises the following steps: A) performing hot forging on a tantalum 5 tungsten cast ingot for three times, wherein a hot forging way is axial upsetting and radial stretching, the upsetting ratio of the axial upsetting is 1.5-2.0, and the stretching ratio of the radial stretching is 0.8-1.0; performing annealing treatment on a tantalum 5 tungsten blank subjected to the hot forging for three times; B) rolling the tantalum 5 tungsten blank subjected to the annealing treatment, wherein the processing rate of rolling is 70-85 percent; C) performing annealing treatment on the tantalum 5 tungsten blank obtained in the step B) to obtain the shaped charge liner tantalum 5 tungsten material. In the process of preparing the tantalum 5 tungsten material, the grain structure inside the prepared tantalum 5 tungsten material is small by adopting the processing methods of the hot forging for three times and the rolling and through controlling parameters in forging and rolling processes, and all mechanical properties are uniform.