The invention discloses a wet-process non-woven fabric manufacturing method. The wet-process non-woven fabric manufacturing method sequentially comprises a web-forming procedure, a vacuum-transferring procedure and a drying procedure of a sizing agent. The web-forming procedure comprises that the sizing agent is adhered on a mesh cage roller to form a fibre web. The vacuum-transferring procedure comprises that a vacuum-transferring roller matched with the mesh cage roller transfers the fibre web to a polyester mesh belt through vacuum suction, wherein the polyester mesh belt is wound around multiple working rollers and the vacuum-transferring roller. The wet-process manufacturing method and the manufacturing equipment which are applicable to 15 - 150 g/m2 non-woven fabric are provided. According to the wet-process non-woven fabric manufacturing method and the manufacturing equipment, a felt is no longer used, and meanwhile the whole production line is shortened.