The invention provides a novel multi-stage treatment process for leaching and compressing household garbage and belongs to the field of treatment of household garbage. The treatment process comprises a two-stage leaching bed reactor, a spiral compression device, a sewage treatment device and a water circulation system, wherein the treatment process comprises the following steps: introducing the garbage into a multi-stage leaching bed, leaching by using supernatant liquid of the sewage treatment device, fully leaching under the stirring action of blades to obtain sewage with high content of organic matters, collecting the sewage, continuing to leach by using a secondary leaching solution, pushing residual garbage into a press filtration part, extruding and dewatering until the water content in the garbage is smaller than 40%. By virtue of the novel multi-stage treatment process, the leaching components are removed in the municipal household garbage in the process; the residual garbage is dewatered and compacted; the organic wastewater generated in the process is aerobically or anaerobically treated; by virtue of combination of a plurality of processes, the purpose of quickly and efficiently reducing volume and quantity of the municipal household garbage is achieved.