The invention belongs to the technical field of domestic rabbit cultivation and relates to a large-scale domestic rabbit breeding farm breeding management system. The large-scale domestic rabbit breeding farm breeding management system comprises an account number login window for the system to conduct login certification on a user and comprising a user name and a password entering port, an information classification module for classifying various information and performing basic setting, an information management module for managing breeding rabbits and breeding information, a group transfer/death and culling management module for recording and data maintenance of the introduction, death and culling and group transfer situations of the breeding rabbits, a rabbit house log management module for recording and data maintenance of materials, epidemic prevention and the disease situation of the breeding rabbits, a breeding management module for managing breeding indexes, hybridization plans, close relative judgment, auxiliary mating and other breeding information and a data input/output module for achieving data input and output. The large-scale domestic rabbit breeding farm breeding management system conducts digital management on domestic rabbit breeding, artificial participation is decreased, and breeding efficiency and accuracy are improved.