基本信息:
- 专利标题： 2-（4-甲基苯基）丙酸的合成方法
- 专利标题（英）：2-(4-methylphenyl)propionic acid syntehsis method
- 申请号：CN201410587819.2 申请日：2014-10-29
- 公开(公告)号：CN104402698A 公开(公告)日：2015-03-11
- 发明人： 王欣荣 , 刘仁华 , 覃秀凤 , 覃春极 , 袁捷才 , 曾蔚 , 何艳 , 杨志华 , 黄婷 , 叶美玲 , 蒋薇薇 , 韦静 , 黄景春 , 覃新善 , 欧阳葭 , 韦志鑫 , 闭武勤
- 申请人： 柳州丰康泰科技有限公司 , 广西柳州化工控股有限公司 , 广西柳化氯碱有限公司
- 申请人地址： 广西壮族自治区柳州市鹿寨县鹿寨镇建中西路100号(工业园区内)
- 专利权人： 柳州丰康泰科技有限公司,广西柳州化工控股有限公司,广西柳化氯碱有限公司
- 当前专利权人： 柳州丰康泰科技有限公司,广西柳州化工控股有限公司,广西柳化氯碱有限公司
- 当前专利权人地址： 广西壮族自治区柳州市鹿寨县鹿寨镇建中西路100号(工业园区内)
- 代理机构： 柳州市荣久专利商标事务所
- 代理人： 韦微
- 主分类号： C07C51/08
- IPC分类号： C07C51/08 ; C07C57/30
The invention relates to a synthesis method of a fine chemical product 2-(4-methylphenyl)propionic acid. According to the method, para-xylene is adopted as a raw material, and a chlorination reaction is carried out, such that a compound I which is p-methylbenzyl chloride is obtained; p-methylbenzyl chloride is subjected to a nitrilation reaction, such that a compound II which is p-methylbenzyl cyanide is adopted; p-methylbenzyl cyanide is subjected to methylation, such that a compound III which is 2-(4-methylphenyl)propionitrile is obtained; and 2-(4-methylphenyl)propionitrile is subjected to hydrolysis acidification, such that a compound IV which is 2-(4-methylphenyl)propionic acid is obtained. The method provided by the invention has the advantages of short process route, low three-waste discharge, low environment pollution, no solid waste production during reaction processes, relatively low production cost, less chemical substances used during reaction processes, less raw material types, easy-to-obtain raw materials, simple operation, high yield, relatively mild process conditions, and the like.
公开/授权文献:
- CN104402698B 2-（4-甲基苯基）丙酸的合成方法 公开/授权日：2016-01-20