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基本信息:
- 专利标题: 利用多巴胺连接氧化石墨烯改善纯钛表面生物活性的方法
- 专利标题(英):Method for improving biological activity of pure titanium surface by using dopamine to be bonded with graphene oxide
- 申请号:CN201410269985.8 申请日:2014-06-17
- 公开(公告)号:CN104141124A 公开(公告)日:2014-11-12
- 发明人: 高颖锟 , 李朝阳 , 朱胜利 , 梁砚琴 , 崔振铎 , 杨贤金
- 申请人: 天津大学
- 申请人地址: 天津市南开区卫津路92号天津大学
- 专利权人: 天津大学
- 当前专利权人: 天津大学
- 当前专利权人地址: 天津市南开区卫津路92号天津大学
- 代理机构: 天津市北洋有限责任专利代理事务所
- 代理人: 王丽
- 主分类号: C23C22/64
- IPC分类号: C23C22/64 ; C23C22/82 ; A61L27/42 ; A61L27/54
The invention relates to a method for improving biological activity of a pure titanium surface by using dopamine to be bonded with graphene oxide. The method comprises the following steps: successively carrying out ultrasonic cleaning on a pure titanium sheet of which the surface roughness Ra is not greater than 1micron by adopting acetone and deionized water; carrying out acid treatment by using a nitric acid, cleaning the pure titanium sheet by the deionized water, and then carrying out alkali treatment on a sample by using sodium hydroxide at 40-80 DEG C; preparing a dopamine-trihydroxymethyl aminomethane solution of which the pH is 8.5; soaking the processed pure titanium sample into the prepared dopamine solution, and standing the sample at room temperature for 12-24 hours; taking out the sample, cleaning the sample by using the deionized water, and drying the sample at room temperature, so as to prepare a titanium/dopamine sample; soaking the titanium/dopamine sample into a graphene oxide water solution and standing the sample at room temperature for 12-24 hours; and cleaning the sample by using the deionized water after taking out the sample, drying the sample at room temperature, so as to prepare a titanium/dopamine/graphene oxide sample. The method is simple to operate, green and pollution-free, mass production can be achieved, and a channel is expanded for surface modification of the titanium material.