基本信息:
- 专利标题： 1,7-间位二碳十硼烷二甲酸三苯基氯化锡配合物及制备方法和应用
- 专利标题（英）：1,7-Meta-dicarbadecaborane diformic acid-triphenyltin chloride complex, as well as preparation method and application thereof
- 申请号：CN201410001758.7 申请日：2014-01-03
- 公开(公告)号：CN103709192A 公开(公告)日：2014-04-09
- 发明人： 李士帅 , 李大成 , 窦建民
- 申请人： 聊城大学
- 申请人地址： 山东省聊城市东昌府区湖南路1号
- 专利权人： 聊城大学
- 当前专利权人： 聊城大学
- 当前专利权人地址： 山东省聊城市东昌府区湖南路1号
- 主分类号： C07F7/22
- IPC分类号： C07F7/22 ; A61P35/00 ; A61P35/02
The invention provides a 1,7-meta-dicarbadecaborane diformic acid-triphenyltin chloride complex, as well as a preparation method and application of the 1,7-meta-dicarbadecaborane diformic acid-triphenyltin chloride complex. The molecular formula of the 1,7-meta-dicarbadecaborane diformic acid-triphenyltin chloride complex is {[(Ph3Sn)(m-CDC)}.(2,2'-Bipyridine)}n(m-CDCH2=1,7-meta-dicarbadecaborane diformic acid; the 1,7-meta-dicarbadecaborane diformic acid-triphenyltin chloride complex has high antitumor activity and can be taken as the raw material to prepare drugs for treating leukemia, human colon cancer and human colorectal adenocarcinoma. Compared with the platinum type anti-cancer drugs commonly used at present, the organic tin complex provided by the invention has the advantages such as high antitumor activity, good lipid solubility, low cost and simple preparation method; and as a result, a new thinking and a new method are provided for developing anticancer drugs.
公开/授权文献:
- CN103709192B 1,7-间位二碳十硼烷二甲酸三苯基氯化锡配合物及制备方法和应用 公开/授权日：2016-03-09
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07F | 含除碳、氢、卤素、氧、氮、硫、硒或碲以外的其他元素的无环，碳环或杂环化合物 |
| ------C07F7/00 | 含周期表第Ⅳ族元素的化合物 |
| --------C07F7/22 | .锡化合物 |