The invention provides a grid security comprehensive evaluation method which includes that a set of complete two-stage in-advance comprehensive evaluation index system and an each-stage security evaluation index calculating method are built aiming at the requirement of grid security operation evaluation, a grid security comprehensive evaluation model based on a gray area correlation analysis method and the game theory is further provided, initial evaluation is conducted on each one-stage index by the model, an obtained evaluation result is subjected to comprehensive evaluation, a correlation coefficient matrix of each one-stage index is determined by adopting the gray area correlation analysis method, weights are obtained by utilizing a game collection model pair analytic hierarchy process (AHP), an artificial neural network (ANN) and an entropy weight method and are objectively combined to obtain a combined weight, initial evaluation is conducted on each one-stage index, the AHP is adopted to determine a one-stage index weight, and the one-stage index weight and an initial evaluation result are subjected to weighing calculation to further obtain a grid security comprehensive evaluation result, namely the grid security quality ordering.