The invention relates to a composition for treating epilepsy, belonging to the technical field of medicines. The compound medicine composition for treating epilepsy is characterized in that the composition contains 3,4-dichlorophenyl-propenoyl-sec.-butylamine and a sodium channel blocker; the sodium channel blocker is selected from medicines such as valproic acid, flunarizine, gabapentin, ethosuximide and mesuximide; and unexpected synergistic effects are gained in treating epilepsy by carrying out compatibility on 3,4-dichlorophenyl-propenoyl-sec.-butylamine and the sodium channel blocker. The composition is provided to improve the compliance of patients and achieve the aim of controlling epileptic seizure, and simultaneously reduces the side effects of a clinical medicine of a central nervous system inhibitor. A safe and effective clinical medicine is provided for epilepsy patients.