基本信息:
- 专利标题： 基于卵裂球分裂和运动的胚胎质量评估
- 专利标题（英）：Embryo quality assessment based on blastomere division and movement
- 申请号：CN201210428780.0 申请日：2007-06-15
- 公开(公告)号：CN103074410A 公开(公告)日：2013-05-01
- 发明人： 尼尔斯·B·拉姆辛 , 于尔根·伯恩特森
- 申请人： 尤尼森斯繁殖技术公司
- 申请人地址： 丹麦奥胡斯
- 专利权人： 尤尼森斯繁殖技术公司
- 当前专利权人： 尤尼森斯繁殖技术公司
- 当前专利权人地址： 丹麦奥胡斯
- 代理机构： 北京派特恩知识产权代理事务所
- 代理人： 武晨燕; 迟姗
- 优先权： PA200600821 2006.06.16 DK; PCT/DK2006/00581 2006.10.16 DK; PA2007/00571 2007.04.19 DK; 60/814,115 2006.06.16 US
- 分案原申请号： 2007800279018 2007.06.15
- 主分类号： C12Q1/02
- IPC分类号： C12Q1/02 ; C12N5/073
The invention concerns a system and method for determining embryo quality comprising monitoring the embryo for a time period, said time period having a length sufficient to comprise at least one cell division period and at least a part of an inter-division period, and determining the length of the at least one cell division period; and/or ii) determining the extent and/or spatial distribution of cellular or organelle movement during the cell division period; and/or iii) determining duration of an inter-division period; and/or iv) determining the extent and/or spatial distribution of cellular or organelle movement during the inter-division period thereby obtaining an embryo quality measure. Thus, the selection of optimal embryos to be implanted after in vitro fertilization (IVF) is facilitated based on the timing, duration, spatial distribution, and extent of observed cell divisions and associated cellular and organelle movement.
公开/授权文献:
- CN103074410B 时间、空间分布以及程度，可促进对体外受精基于卵裂球分裂和运动的胚胎质量评估 (IVF)后被植入的最佳胚胎的选择。 公开/授权日：2016-12-07