The invention discloses a grounding wire clamp with a universal joint, which can rotate at any angle and is suitable for conductors in various geometric shapes. The grounding wire clamp with the universal joint comprises a guide rail, wherein the guide rail is connected with an upper line pressing plate and a lower line pressing plate through connecting flexible wires; the lower end of the guide rail has a bracket which is perpendicular to the guide rail; the right part of the bracket has a grounding wire hole; the upper line pressing plate and the lower line pressing plate are connected with the grounding wire hole through connecting flexible wires; the upper line pressing plate and the lower line pressing plate are connected with a dual-spiral screw rod with a dual-spiral rod shaft through threads; a shaft hole is formed in the bracket; the dual-spiral rod shaft passes through the shaft hole and is connected with the universal joint; a spring pin is fixedly connected with the penetrated end of the dual-spiral rod shaft; a soft shaft is connected with the universal joint; and the lower end of the universal joint is connected with an operating rod.