The invention discloses an application of a nerve-cultivating and brain-soothing medicinal composition to a medicament for treating pseudobulbar palsy. A nerve-cultivating and brain-soothing capsule is prepared from a rehmannia decoction and five-element powder, and has the effects of tonifying the kidney, replenishing essence, expelling wind and eliminating collateral channels. In a prescription, prepared rehmannia rhizome, prepared multiflower knotweed tuber, turtle shell, asparagus and desertliving cistanche are used for nourishing yin and supplementing kidney; hairy deerhorn and cassia bark are used for warning the kidney to invigorate yang; scorpio and earthworm are used for invading collateral channels, expelling wind and eliminating evil; leech and red paeony root are used for promoting blood circulation to dispel blood stasis; and red paeony root, fructus crataegi and liquoric root are used for protecting spleen and lung and coordinating the medicaments. As proved by clinical tests, the nerve-cultivating and brain-soothing capsule has a remarkable curative effect on pseudobulbar palsy.