基本信息:
- 专利标题： 用于传递治疗剂的以环糊精为基础的聚合物
- 专利标题（英）：Cyclodextrin-based polymers for therapeutics delivery
- 申请号：CN201110329366.X 申请日：2003-09-04
- 公开(公告)号：CN102516417A 公开(公告)日：2012-06-27
- 发明人： 程建军 , M·E·戴维斯 , K·T·金
- 申请人： 天蓝制药公司
- 申请人地址： 美国马萨诸塞州
- 专利权人： 天蓝制药公司
- 当前专利权人： 天蓝制药公司
- 当前专利权人地址： 美国马萨诸塞州
- 代理机构： 北京市中咨律师事务所
- 代理人： 安佩东; 黄革生
- 优先权： 60/408,855 2002.09.06 US; 60/422,830 2002.10.31 US; 60/451,998 2003.03.04 US
- 分案原申请号： 038248298 2003.09.04
- 主分类号： C08B37/16
- IPC分类号： C08B37/16 ; A61K47/48
The invention refers to cyclodextrin-based polymers for therapeutics delivery. More specifically, the present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distribution kits containing or relating to the polymeric compounds described herein.
公开/授权文献:
- CN102516417B 用于传递治疗剂的以环糊精为基础的聚合物 公开/授权日：2014-12-10
IPC结构图谱:
| C | 化学；冶金 |
| --C08 | 有机高分子化合物；其制备或化学加工；以其为基料的组合物 |
| ----C08B | 多糖类；其衍生物 |
| ------C08B37/00 | 不包括在C08B1/00至C08B35/00组内的多糖类的制备；其衍生物 |
| --------C08B37/16 | .环糊精；它的衍生物 |