
基本信息:
- 专利标题: 黄绵马酸AB在制备抗肿瘤和抗病毒药物的用途
- 专利标题(英):Application of flavaspidic acid AB to preparation of antitumor and antivirus medicament
- 申请号:CN201010266528.5 申请日:2010-08-30
- 公开(公告)号:CN102379863A 公开(公告)日:2012-03-21
- 发明人: 曹丽 , 斯建勇 , 潘瑞乐
- 申请人: 中国医学科学院药用植物研究所
- 申请人地址: 北京市海淀区马连洼北路151号
- 专利权人: 中国医学科学院药用植物研究所
- 当前专利权人: 中国医学科学院药用植物研究所
- 当前专利权人地址: 北京市海淀区马连洼北路151号
- 主分类号: A61K31/122
- IPC分类号: A61K31/122 ; A61P35/00 ; A61P31/12 ; A61P31/14
The invention discloses a plant-derived monomeric compound, i.e., flavaspidic acid AB for effectively treating and preventing porcine reproductive and respiratory syndrome and resisting tumors. As proved by an in-vitro antitumor experiment, the flavaspidic acid AB has remarkable inhibitory actions on a plurality of malignant tumors such as cervical cancer, breast cancer, gastric cancer, lung cancer and liver cancer; and as proved by an in-vitro antivirus experimental result, the flavaspidic acid AB (20 and 40 mug/ml) can be used for effectively inhibiting porcine reproductive and respiratory syndrome viruses 0 hour, 1 hour, 2 hours and 3 hours after cell exposure, can act at the early stage of porcine reproductive and respiratory syndrome virus infection, and has the effect of inhibiting duplication or budding after virus uncoating. The flavaspidic acid AB can be taken as a medicament or a lead compound for preventing and treating tumors and porcine reproductive and respiratory syndrome infection.
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K31/00 | 含有机有效成分的医药配制品 |
--------A61K31/045 | .羟基化合物,例如醇类;其盐类,例如醇化物 |
----------A61K31/122 | ..含直接与环相连的氧原子的,例如醌类、维生素K1、地蒽酚 |