The invention discloses a Chinese medicine weight-losing preparation comprising an external preparation and an oral preparation and a preparation method thereof. The Chinese medicine weight-losing preparation comprises an external preparation and an oral preparation. The external preparation comprises the following raw materials in parts by weight: 10-20 parts of Chinese rhubarb, 7-15 parts of rhizome of oriental water plantain, 15-30 parts of folium sennae, 10-20 parts of lotus leaf, 3-6 parts of semen coicis, 10-20 parts of fried cassia seed, 5-10 parts of dark malt, 5-10 parts of charred fructus crataegi, 5-10 parts of charred medicated leaven, 5-10 parts of trifoliate orange fruit and 2-4 parts of camphor. The oral preparation comprises the following raw materials in parts by weight: 10-50 parts of glucomannan, 1-10 parts of hawthorn flavonoids, 5-20 parts of wheat gluten powder and 1-5 parts of xylitol. During the preparation, the raw materials are crushed to prepare the external preparation and the oral preparation. The external preparation and the oral preparation are combined to be used simultaneously with better effect and no side effects.