The invention relates to a vertical-type fatigue test device used for a vertical tube, comprising a vertical-type tower, top acting cylinders, a bottom acting cylinder, a horizontal acting cylinder and a horizontal sand tank. During simulating the fatigue test of the upper part of the vertical tube, the vertical-type tower is transversely fixed with a rigid upper base plate, two top acting cylinders are connected with the rigid upper base plate, the piston rods of the two top acting cylinders are hinged with a rigid connecting plate, the lower end of the rigid connecting plate is fixedly connected with a test vertical tube; and the lower end of the test vertical tube is supported by and connected with the bottom acting cylinder, the horizontal acting cylinder is fixed at the position corresponding to the middle bottom part of the test vertical tube, and the piston rod of the horizontal acting cylinder can reach and touch the test vertical tube. During simulating the fatigue test of the lower part of the vertical tube, the lower end of the rigid connecting plate is hinged with the test vertical tube, the other end of the vertical tube is inserted into the horizontal sand tank and is fixed by a fixing device; and the sand tank is filled with sand and water. The test device provided by the invention can simulate not only the fatigue state of the upper part of the vertical tube but also the fatigue state of the lower part of the vertical tube, thus the aim of a multipurpose test device is achieved.