The invention belongs to the field of mechanical connection structures, which relates to a memory protection device and a computer therewith. The memory protection device is arranged on a memory connecting seat and a memory, and can prevent dust, looseness and oxidation for the memory. The memory protection device is characterized in that the memory is inserted in a slot of the memory connecting seat, and is fixed to the memory connecting seat through fasteners on both ends of the memory connecting seat. The memory protection device comprises an insulating heat-conducting bar; the insulating heat-conducting bar is connected to the upper ends of two side slot walls of the memory connecting seat, and covers the heat radiating holes of the two side slot walls of the memory connecting seat. The memory protection device also comprises a heat-conducting cover, and the heat-conducting cover covers the memory and is in contact with electronic components on the memory in an insulating manner; the upper end of the heat-conducting cover is closed, and the lower end is opened; the upper parts of both ends of the heat-conducting cover are closed, and are connected with both ends of a circuit board of the memory in a clamping manner; the lower parts of both ends of the heat-conducting cover are open; both sides of the heat-conducting cover are in a T shape; and the lower end of the heat-conducting cover is in contact with the insulating heat-conducting bar.