基本信息:
- 专利标题： 含有猪细小病毒VP2和生长抑素嵌合蛋白的病毒样颗粒
- 专利标题（英）：Virus-like particle containing porcine parvovirus VP2 and somatostatin chimeric protein
- 申请号：CN201010240974.9 申请日：2010-07-30
- 公开(公告)号：CN101955917A 公开(公告)日：2011-01-26
- 发明人： 侯红岩 , 张雪花 , 郑其升 , 侯继波 , 陈瑾 , 侯风香 , 薛刚 , 李卓 , 刘超
- 申请人： 国家兽用生物制品工程技术研究中心
- 申请人地址： 江苏省南京市孝陵卫钟灵街50号
- 专利权人： 国家兽用生物制品工程技术研究中心
- 当前专利权人： 江苏省农业科学院
- 当前专利权人地址： 江苏省南京市孝陵卫钟灵街50号
- 代理机构： 南京众联专利代理有限公司
- 代理人： 王荷英
- 主分类号： C12N7/04
- IPC分类号： C12N7/04 ; C12N7/01 ; C12N15/12 ; C12N15/35 ; C12N15/866 ; A61K39/00 ; A61K39/23 ; A61P31/20 ; A61P43/00
The invention relates to the field of gene engineered vaccine and provides a virus-like particle containing porcine parvovirus VP2 and somatostatin chimeric protein. The virus-like particle containing porcine parvovirus VP2 and somatostatin chimeric protein is prepared by the following steps of: acquiring a target gene; constructing and identifying a recombined transfer vector pFast-SS4-VP2; constructing and identifying a recombined shuttle vector rBacmid-SS4-VP2; obtaining stable recombined baculovirus rBac-SS4-VP2; and infecting the rBacmid-SS4-VP2 to sf-9 insect cell to obtain a target product. The virus-like particle can be applied to preparing a vaccine for preventing porcine-infecting parvovirus and improving the growing speed of pigs, not only can prevent the porcine-infecting parvovirus, bus also can improve the growing speed of the pigs. The invention also provides application of the virus-like particle to preparing the vaccine for preventing the porcine-infecting parvovirus and improving the growing speed of the pigs.
公开/授权文献:
- CN101955917B 含有猪细小病毒VP2和生长抑素嵌合蛋白的病毒样颗粒 公开/授权日：2012-08-22