基本信息:
- 专利标题： 梅花参中新的抗肿瘤化合物Ananaside C
- 专利标题（英）：Novel antineoplastic compound Ananaside C in thelenota ananas
- 申请号：CN200810061262.3 申请日：2008-03-26
- 公开(公告)号：CN101245092A 公开(公告)日：2008-08-20
- 发明人： 巫军
- 申请人： 巫军
- 申请人地址： 浙江省宁波市保税区创业大厦509室
- 专利权人： 巫军
- 当前专利权人： 巫军
- 当前专利权人地址： 浙江省宁波市保税区创业大厦509室
- 主分类号： C07J71/00
- IPC分类号： C07J71/00 ; C07J75/00 ; A61K31/58 ; A61P35/00 ; A61K35/56
The invention relates to the field of medical technology, in particular to an anti-cancer compound Ananaside C which is separated from thelenota ananas, and the molecular formula is C41H63O17SNa. The chemical structure and the spatial configuration of the compound are determined by various modern spectral analysises, in particular to the comprehensive analysis by applying the advanced two-dimensional nuclear magnetic resonance spectra and high resolution mass spectra. In vitro anti-tumor trials show that the compound has significant inhibition function on A-549 lung cancer and IA-9 ovarian cancer and other 8 kinds of tumor cell strains. The compound can provide a lead compound for the development of new anti-tumor drugs, which has important values for the development and the utilization of the marine medicinal and biological resources of China.