The invention relates to a decoloration refining process of total saponins of panax notoginseng leaf ions exchange resin and a resin regeneration method. The decoloration refining process is: first cation-exchange the dilute alcohol water solution of the total saponins of panax notoginseng leaf with resin column and then anion-exchange resin column to decolorate, and when the decoloration is completed, shower the resin column to reduce the loss of total saponins of panax notoginseng leaf and then depressing and steaming the solution and the shower solution, and the product is formed when the leftover is dried. The failure resin can regenerate to get the decoloration ability. The invention method can improve the purity of the produced total saponins of panax notoginseng leaf to more than 90 percent, and improve the exterior color and further be crystallized and purified to get products with high purity. The invention of ion-exchange resin decoloration refining process does not lead into other chemical matters in the process of total saponins of panax notoginseng leaf decoloration, thus avoiding polluting the product again in the process of decoloration. The decoloration process is easy, and the cost is low, while the decoloration effect is obvious and the equipment structure is simple.