基本信息:
- 专利标题： BIO-PRODUCTION OF LENTIVIRAL VECTORS
- 申请号：CA2985828 申请日：2016-05-12
- 公开(公告)号：CA2985828A1 公开(公告)日：2016-11-17
- 发明人： LEE CHI-LIN , BARTLETT JEFFREY S
- 申请人： CALIMMUNE INC
- 专利权人： CALIMMUNE INC
- 当前专利权人： CALIMMUNE INC
- 优先权： US201562161133 2015-05-13; US201562161152 2015-05-13
- 主分类号： C12N15/867
- IPC分类号： C12N15/867 ; A61K35/76 ; C12N5/10 ; C12N7/00 ; C12N7/02 ; C12N15/63 ; C12N15/85
摘要：
The present disclosure provides a method of generating a stable producer cell line. The generation of stable producer cell lines, such as those provided in accordance with the present invention, increases the reproducibility and ease of creating high titer lentiviral stocks while easing biosafety concerns and the variation in expressed envelope proteins defines the tropism of the generated virus. The present disclosure also provides for a novel lentiviral transfer vector plasmid.
公开/授权文献:
- CA2985828C BIO-PRODUCTION OF LENTIVIRAL VECTORS 公开/授权日：2020-07-14