基本信息:
- 专利标题： NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION
- 申请号：CA2720846 申请日：2009-04-14
- 公开(公告)号：CA2720846A1 公开(公告)日：2009-11-05
- 发明人： BEIGELMAN LEONID , WANG GUANGYI , BUCKMAN BRAD O , STOYCHEVA ANTITSA DIMITROVA
- 申请人： INTERMUNE INC
- 专利权人： INTERMUNE INC
- 当前专利权人： INTERMUNE INC
- 优先权： US4521408 2008-04-15; US14833709 2009-01-29; US10985608 2008-10-30; US11791608 2008-11-25; US4521908 2008-04-15
- 主分类号： C07D285/30
- IPC分类号： C07D285/30 ; A61K31/5415 ; A61P31/14 ; C07D417/04 ; C07D417/14 ; C07D471/04 ; C07D487/04 ; C07D491/12
摘要：
The embodiments provide compounds of the general Formula I, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D285/00 | 杂环化合物，有氮原子和硫原子作为仅有的杂环原子的环，不包含在C07D275/00至C07D283/00组中 |
| --------C07D285/01 | .五元环 |
| ----------C07D285/16 | ..噻二嗪；氢化噻二嗪 |
| ------------C07D285/18 | ...1,2,4-噻二嗪；氢化1,2,4-噻二嗪 |
| --------------C07D285/20 | ....和碳环或碳环系稠合 |
| ----------------C07D285/22 | .....和1个六元环稠合 |
| ------------------C07D285/24 | ......有氧原子直接连在环硫原子上 |
| --------------------C07D285/26 | .......在位置6或7，被氨磺酰基或取代的氨磺酰基取代 |
| ----------------------C07D285/30 | ........有被杂原子取代的烃基连在位置3上 |