基本信息:
- 专利标题： Multivalent binding composition for nucleic acid analysis
- 申请号：AU2020285657 申请日：2020-05-22
- 公开(公告)号：AU2020285657B2 公开(公告)日：2022-10-06
- 发明人： ARSLAN SINAN , HE MOLLY , KELLINGER MATTHEW , LEVIEUX JAKE , PREVITE MICHAEL , ZHAO JUNHUA , ZHANG SU , LOPEZ TYLER
- 申请人： ELEMENT BIOSCIENCES INC
- 专利权人： ELEMENT BIOSCIENCES INC
- 当前专利权人： ELEMENT BIOSCIENCES INC
- 优先权： US201962852876 2019-05-24; US201962897172 2019-09-06
- 主分类号： C12Q1/6869
- IPC分类号： C12Q1/6869
摘要：
Multivalent binding compositions including a particle-nucleotide conjugate having a plurality of copies of a nucleotide attached to the particle are described. The multivalent binding compositions allow one to localize detectable signals to active regions of biochemical interaction, e.g., sites of protein-protein interaction, protein-nucleic acid interaction, nucleic acid hybridization, or enzymatic reaction, and can be used to identify sites of base incorporation in elongating nucleic acid chains during polymerase reactions and to provide improved base discrimination for sequencing and array based applications.
公开/授权文献:
- AU2020285657A1 Multivalent binding composition for nucleic acid analysis 公开/授权日：2021-11-18