基本信息:
- 专利标题： Oxyntomodulin analogs
- 申请号：AU2009340439 申请日：2009-12-18
- 公开(公告)号：AU2009340439A1 公开(公告)日：2011-09-15
- 发明人： CARRINGTON PAUL E , EIERMANN GEORGE J , MARSH DONALD J , METZGER JOSEPH M , ALESSANDRO POCAI , RANABIR SINHA ROY , ELISABETTA BIANCHI , PAOLO INGALLINELLA , ANTONELLO PESSI , ALESSIA SANTOPRETE , ELENA CAPITO , RICHARD DIMARCHI , BRIAN WARD
- 申请人： UNIV INDIANA RES & TECH CORP , ANGELETTI P IST RICHERCHE BIO , MERCK SHARP & DOHME
- 专利权人： UNIV INDIANA RES & TECH CORP,ANGELETTI P IST RICHERCHE BIO,MERCK SHARP & DOHME
- 当前专利权人： UNIV INDIANA RES & TECH CORP,ANGELETTI P IST RICHERCHE BIO,MERCK SHARP & DOHME
- 优先权： US2009034448 2009-02-19
- 主分类号： A61K38/00
- IPC分类号： A61K38/00
摘要：
Peptide analogs of oxyntomodulin (OXM, glucagon-37), which have been modified to be resistant to cleavage and inactivation by dipeptidyl peptidase IV (DPP-IV) and to increase in vivo half-life of the peptide analog while enabling the peptide analog to act as a dual GLP-1/glucagon receptor (GCGR) agonist, are described. The peptide analogs are useful for treatment of metabolic disorders such as diabetes and obesity.
公开/授权文献:
- AU2009340439B2 Oxyntomodulin analogs 公开/授权日：2015-07-16
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K38/00 | 含肽的医药配制品 |